Abstract

Cancer is a disease marked by uncontrolled growth and division of cells, making tumors. If the tumor spread is not controlled, it can result in mortality. Cancer is caused by the both external factors (tobacco, chemicals, radiation, and infectious organisms) and internal factors (inherited mutations, hormones, immune conditions, and mutations that occur from metabolism). 1 Cancer can occur in the breast, lungs, colon, blood cells and etc. Cancers are similar in some ways, but different in growth and spread routes.2 Normal cells are divided in a regular routine order. They die when become damaged and new cells take their place.3 When cancer cells spread in the body, it is called metastasis. Many new and effective therapies are currently being used to treat cancer. Among the new ways to battle cancer, chemotherapy based on peptides has attracted a great interest and considerable attention. This is due to the unique advantages of peptides, such as having low molecular weights, the ability to specifically target tumor cells, and low toxicity in normal tissues. During the last decade, peptides have gained a wide range of applications in medicine, drug delivery and biotechnology.4