Abstract

COVID-19 infection since 2019 is a global pandemic that has challenged the health care system worldwide. The symptoms of coronavirus are usually fever, cough, sore throat, breathlessness, fatigue and malaise among others. The disease is mild in most people; in some may progress to pneumonia, acute respiratory distress syndrome and multi organ dysfunction. Most infected patients are asymptomatic or have only mild symptoms. (China Novel Coronavirus I, 2019).The lung is the main affected organ in severe coronavirus disease caused by the novel coronavirus and undergoes an acute pneumonia process accompanied by diffuse alveolar injury, inflammatory infiltrates, and microvascular thrombosis that is the leading cause of death in the vast majority of patients. (Yuki et al., 2020). Although the recommended treatments with drugs for COVID-19 and its side effects are antiviral, antithrombotic, anti-inflammatory, antibiotic, anti-malarial, immunomodulatory, and anticoagulant, there is currently a number of drugs used for treatments of this virus, but their safety and efficacy are under investigation (Wu et al., 2020).Many of the immune responses and respiratory symptoms of COVID-19 patients are common with other respiratory viral diseases (Yuki et al., 2020). In Iranian traditional medicine, several medicinal plants with antiviral, imunomodelating, anti-inflammatory, antioxidant and antimicrobial properties are known to improve pulmonary and systemic symptoms of viral infections, which may be effective in preventing and improving the symptoms of COVID infection (Kenari et al., 2021). Herbal product under the brand name Imfluna is one of the herbal mixtures used similarly by some other herbal ingredients  (Manavari SHR, 1386).  Although the recommended treatments with drugs for COVID-19 and its side effects are antiviral, antithrombotic, anti-inflammatory, antibiotic, anti-malarial, immunomodulatory, and anticoagulant, there is currently a number of drugs used for treatments of this virus, but their safety and efficacy are under investigation (Wu et al., 2020).Many of the immune responses and respiratory symptoms of COVID-19 patients are common with other respiratory viral diseases (Yuki et al., 2020). In Iranian traditional medicine, several medicinal plants with antiviral, imunomodelating, anti-inflammatory, antioxidant and antimicrobial properties are known to improve pulmonary and systemic symptoms of viral infections, which may be effective in preventing and improving the symptoms of COVID infection (Kenari et al., 2021). Herbal product under the brand name Imfluna is one of the herbal mixtures used similarly by some other herbal ingredients  (Manavari SHR, 1386).